Isotopically Labeled Compounds
Medchemexpress LLC Dimethyl adipate-d8 | 52089-64-2 | MFCD12022192 | 98.0% | 182.24 | C8H6D8O4 | 100 MG
Dimethyl adipate-d8 is a deuterium-labeled analogue of dimethyl adipate used as an isotopically labeled reference standard for analytical chemistry. It is intended for use as an internal standard in mass spectrometry and chromatographic assays, offering predictable chromatographic behavior with a distinct mass shift.
- Deuterated analogue with eight deuterium atoms, providing clear mass separation.
- High isotopic enrichment for reliable internal standard performance.
- High chemical purity suitable for analytical workflows.
- Multiple small package sizes available for laboratory-scale use.
- Stable under recommended storage conditions for consistent results.
Medchemexpress LLC Sorafenib-d3 (Donafenib; Bay 43-9006-d3) | 1130115-44-4 | 99.57% | 467.84 | 25 MG
Sorafenib-d3 (Donafenib) is a deuterated compound of Sorafenib, recognized as the first deuterium-generation tumor suppressor small molecule. Sorafenib itself is a multikinase inhibitor with IC50s of 6 nM for Raf-1, 20 nM for B-Raf, and 22 nM for VEGFR-3. This compound is intended for research use only. Potential advantages of deuterated compounds like Sorafenib-d3 include:
- Extends the in vivo half-life.
- Improves oral bioavailability.
- Enhances metabolic characteristics.
- Improves drug safety.
- Preserves therapeutic properties.
Medchemexpress LLC Ethyl 4-hydroxybenzoate-d4 | 1219795-53-5 | 170.20 | C9H6D4O3 | 10 MG
Ethylparaben-d4 is the deuterium-labeled analog of ethyl 4-hydroxybenzoate supplied for research use as an isotopically labeled internal standard or tracer for quantitative analysis by NMR, GC-MS, and LC-MS. It contains four deuterium atoms (d4) to enable mass discrimination and accurate quantitation.
- Deuterium-labeled internal standard for quantitative analysis.
- Suitable for NMR, GC-MS, and LC-MS applications.
- Molecular formula C9H6D4O3 and molecular weight 170.20.
- Available in small analytical quantities (commonly 1 mg, 5 mg, 10 mg).
- For research use only; not for human or clinical use.
Medchemexpress LLC Pefloxacin-d3 | 2733455-58-6 | 99.4% | 336.38 g/mol | C17H17D3FN3O3 | 10 MG
Pefloxacin-d3 is the deuterium-labeled analogue of the fluoroquinolone antibiotic pefloxacin. It inhibits DNA gyrase and interferes with topoisomerase I-mediated DNA relaxation, and is supplied as a high-purity stable isotope for analytical and research use.
- Deuterium-labeled internal standard for quantitative analysis.
- High purity to support analytical accuracy.
- Suitable as a tracer in infection and pharmacokinetic studies.
- Provided as a laboratory-grade powder for analytical workflows.
Medchemexpress LLC Nizatidine-d3 | 1246833-99-7 | MFCD32641299 | 98.8% | 334.48 | C12H18D3N5O2S2 | 10 MG
Nizatidine-d3 is the deuterium-labeled form of nizatidine supplied as an isotope-labeled reference standard for research applications, including mass spectrometry, pharmacokinetic, and metabolic studies. It is intended for use as a labeled internal standard to support quantitative analytical workflows.
- Deuterium-labeled internal standard for mass spectrometry assays.
- High chemical purity: 98.8%.
- CAS number 1246833-99-7 for unambiguous identification.
- Available in small-mass packaged quantities suitable for analytical use.
- Useful for ADME, PK/PD, and quantitative analytical studies.
Medchemexpress LLC L-serine-13C3,15N | 202407-34-9 | MFCD00144678 | 99.9% | 109.06 | 13C3H7 15NO3 | 10 MG
L-Serine-13C3,15N is a stable isotope-labeled L-serine in solid form, with three 13C atoms and one 15N atom. It is supplied as a high-purity analytical standard for mass spectrometry, metabolic tracing, and biochemical assays.
- Stable isotope-labeled reference standard for MS and tracer studies.
- Isotopic enrichment: three 13C atoms and one 15N atom.
- High purity (99.9%) suitable for quantitative analysis.
- Molecular weight 109.06 and CAS number 202407-34-9 for unambiguous identification.
- Physical form: solid powder; soluble in water.
- Typical applications include internal standard, metabolic flux analysis, and pathway tracing.
Medchemexpress LLC 2-Carboxyphenol-d4 | 78646-17-0 | 99.8% | 142.15 g·mol⁻¹ | C7H2D4O3 | 1 MG
2-Carboxyphenol-d4 is a deuterium-labeled analogue of 2-carboxyphenol intended for use as a tracer or internal standard in quantitative analytical methods. The d4 labeling improves accuracy for isotope-dilution experiments and facilitates detection by NMR, GC-MS, and LC-MS. The compound is provided in milligram-scale packages with high reported purity.
- Deuterium-labeled (d4) for isotopic tracing
- High reported purity (99.83%)
- Suitable as an internal standard for NMR, GC-MS, and LC-MS
- Molecular formula C7H2D4O3; molecular weight 142.15 g·mol⁻¹
- Supplied in milligram-scale packages for analytical use
Medchemexpress LLC Methomyl-d3 | 1398109-07-3 | C5H7D3N2O2S | 1 MG
Methomyl-d3 is a deuterium labeled compound primarily used as a tracer and as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes such as hydrogen, carbon, and other elements into drug molecules, particularly deuterium, is used for quantitation during drug development and has shown potential in influencing the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC L-leucine-5,5,5-d3 | 87828-86-2 | 99.9% | 134.19 g/mol | C6H10D3NO2 | 10 MG
L-leucine-d3 is the deuterium-labeled form of the essential branched-chain amino acid L-leucine, provided as a stable isotope reagent for research applications such as metabolic tracing and mass spectrometry. It features high isotopic enrichment and is for research use only.
- Deuterium labeled at the methyl group (5,5,5-d3).
- High purity, reported as 99.93% (rounded to 99.9%).
- CAS number 87828-86-2 for chemical identification.
- Suitable for use in mass spectrometry and metabolic tracing experiments.
- Available in small research pack sizes, including 10 mg.
Medchemexpress LLC Cholic acid-d5 | 53007-09-3 | MFCD08702879 | 98.0% | 413.60 | C24H35D5O5 | 10 MG
Cholic acid-d5 is the deuterium-labeled analogue of cholic acid supplied for use as an internal standard or tracer in analytical workflows. It supports quantitative method development and routine analyses in NMR, GC-MS, and LC-MS, and is intended for research use only.
- Deuterium-labeled internal standard for quantitative NMR, GC-MS, and LC-MS.
- High purity (98.0%).
- Molecular formula C24H35D5O5; molecular weight 413.60.
- CAS number 53007-09-3.
- Provided as a 10 mg vial; store protected from light and under inert atmosphere.
- For research use only; not for human or animal therapeutic use.
Medchemexpress LLC CH5468924-d4 (Alectinib metabolite M-4-d4) | >98.0% | 460.6 g/mol | C28H28D4N4O2 | 2.5mg
CH5468924-d4 (Alectinib Metabolite M-4-d4) is the deuterium labeled CH5468924
Medchemexpress LLC Geraniol-d6 (major) | 1660976-93-1 | 95.3% | 160.29 | C10H12D6O | 1mg
Geraniol-d6 (Major) is the deuterated labeled Geraniol (Major) Geraniol is an olefin terpene with oral activity Geraniol inhibits cell proliferation and promotes apoptosis Geraniol has antibacterial antifungal antioxidant anti-inflammatory and antitumor activities Geraniol can be used to study diabetes[1][2][3][4][5]
Medchemexpress LLC 2-mercaptoethanol-d6 | 203645-37-8 | 99.7% | 84.17 g/mol | C2D6OS | 5mg
2-Mercaptoethanol-d6 is deuterium labeled 2-Mercaptoethanol[1]